STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (255 aa)    
Predicted Functional Partners:
ADK81528.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR000991:IPR001962:IPR001674:IPR017926:IPR 004739; KEGG: aae:aq_236 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; asparagine synthase; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; Asparagine synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
    
 0.955
ADK80529.1
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR015875:IPR001093:IPR000644:IPR018529; KEGG: clo:HMPREF0868_0954 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; SPTR: IMP dehydrogenase/GMP reductase; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase.
    
 0.943
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: tde:TDE2080 cytidylate kinase/ribosomal protein S1; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase/ribosomal protein S1; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
    
 0.930
ADK82258.1
AAA ATPase; COGs: COG0572 Uridine kinase; InterPro IPR003593; KEGG: tde:TDE2289 phosphoribulokinase/uridine kinase family protein; SMART: AAA ATPase; SPTR: Uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family.
 
 
 0.930
ADK80654.1
COGs: COG0035 Uracil phosphoribosyltransferase; KEGG: tde:TDE1612 phosphoribosyl transferase domain-containing protein; SPTR: Phosphoribosyl transferase domain protein.
  
  
 0.929
ADK83230.1
COGs: COG0213 Thymidine phosphorylase; InterProIPR017459:IPR000312:IPR013102:IPR017872:IPR 018090:IPR000053; KEGG: drm:Dred_1101 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; PRIAM: Pyrimidine-nucleoside phosphorylase; SPTR: Thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside ph [...]
    
 0.929
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
 
 
  0.928
ADK81493.1
Fumarate lyase; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362:IPR003031:IPR020557; KEGG: tde:TDE1499 adenylosuccinate lyase, putative; PFAM: fumarate lyase; SPTR: Adenylosuccinate lyase, putative; PFAM: Lyase.
    
 0.928
ADK82848.1
COGs: COG0528 Uridylate kinase; InterPro IPR001048:IPR011818; KEGG: tde:TDE2085 uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Amino acid kinase family protein; TIGRFAM: uridylate kinase; PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase, putative.
     
 0.927
ADK80562.1
COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR001754:IPR011995; KEGG: tde:TDE2110 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2.
    
 0.926
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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