Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADK82306.1InterPro IPR000551; KEGG: tde:TDE0082 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Transcriptional regulator, MerR family; PFAM: MerR family regulatory protein. (121 aa)    
Predicted Functional Partners:
ADK82305.1
KEGG: tde:TDE1533 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.789
ADK82303.1
KEGG: rsh:Rsph17029_3404 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.782
ADK82304.1
TPR repeat-containing protein; InterProIPR019734:IPR006597:IPR013026:IPR001440:IPR 011717; KEGG: rmr:Rmar_1517 outer membrane assembly lipoprotein YfiO; PFAM: TPR repeat-containing protein; Sel1 domain protein repeat-containing protein; Tetratricopeptide TPR_4; SPTR: Outer membrane assembly lipoprotein YfiO.
       0.782
ADK82301.1
COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: pca:Pcar_1506 biopolymer transport protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein; PFAM: Biopolymer transport protein ExbD/TolR.
     
 0.743
ADK82300.1
Hypothetical protein; KEGG: prw:PsycPRwf_1514 TonB family protein; SPTR: TonB family protein; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain.
       0.741
ADK82302.1
MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: bhy:BHWA1_00538 biopolymer transport protein ExbB; PFAM: MotA/TolQ/ExbB proton channel; SPTR: Biopolymer transport protein ExbB; PFAM: MotA/TolQ/ExbB proton channel family.
       0.741
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
       0.724
ADK82308.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
     
 0.690
ADK82299.1
Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834; KEGG: bre:BRE_516 putative hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Putative hydrolase; PFAM: haloacid dehalogenase-like hydrolase.
       0.687
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.582
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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