STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADK82384.1Serine--pyruvate transaminase; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: mlo:mlr6806 aspartate aminotransferase; PFAM: aminotransferase class V; PRIAM: Serine--pyruvate transaminase; SPTR: Aspartate aminotransferase; PFAM: Aminotransferase class-V. (383 aa)    
Predicted Functional Partners:
ADK83304.1
Phosphoenolpyruvate phosphomutase; COGs: COG2513 PEP phosphonomutase; InterPro IPR012698; KEGG: rme:Rmet_1808 2,3-dimethylmalate lyase; SPTR: Phosphoenolpyruvate phosphomutase; TIGRFAM: phosphoenolpyruvate phosphomutase; TIGRFAM: phosphoenolpyruvate phosphomutase.
 
  
 0.588
ADK83303.1
Phosphonopyruvate decarboxylase; COGs: COG4032 thiamine-pyrophosphate-binding protein; InterPro IPR011766:IPR017684; KEGG: bmj:BMULJ_04038 thiamine pyrophosphate-requiring 3-phosphonopyruvate decarboxylase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: Phosphonopyruvate decarboxylase; TIGRFAM: phosphonopyruvate decarboxylase; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: phosphonopyruvate decarboxylase.
 
 
 0.546
ADK80013.1
Alanyl-tRNA synthetase, class IIc; COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR018164:IPR012947:IPR018165; KEGG: tte:TTE0934 metal-dependent hydrolase; PFAM: Alanyl-tRNA synthetase, class IIc-like; Threonyl/alanyl tRNA synthetase SAD; SPTR: Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain; PFAM: tRNA synthetases class II (A).
 
  
 0.527
ADK80598.1
COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262:IPR012133:IPR017934; KEGG: dvl:Dvul_0528 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: Dehydrogenase, FMN-dependent family; PFAM: FMN-dependent dehydrogenase.
  
 0.499
purD
Phosphoribosylamine/glycine ligase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate; Belongs to the GART family.
  
  
 0.491
ADK81442.1
COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: sus:Acid_3816 glutamate synthase (NADH) large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (NADH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.478
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.441
ADK82291.1
COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR011761:IPR020562:IPR020561:IPR020560:IPR 000115:IPR020559; KEGG: eel:EUBELI_00551 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phos [...]
  
  
 0.422
ADK82385.1
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR004090; KEGG: tte:TTE0680 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: Methyl-accepting chemotaxis protein; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain.
       0.422
ADK82386.1
Domain of unknown function DUF1745; COGs: COG3287 conserved hypothetical protein; InterPro IPR013702:IPR019494; KEGG: ppd:Ppro_3141 hypothetical protein; PFAM: domain of unknown function DUF1745; FIST C domain; SPTR: Putative uncharacterized protein; PFAM: FIST C domain; FIST N domain.
       0.422
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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