STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADK82511.1Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR000005:IPR020449; KEGG: cce:Ccel_1228 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, Ara [...] (535 aa)    
Predicted Functional Partners:
ADK82512.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR003594:IPR010559; KEGG: hau:Haur_2122 histidine kinase internal region; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: Histidine kinase internal region; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.982
ADK80490.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594:IPR005467; KEGG: bha:BH3447 two-component sensor histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.911
ADK82365.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: cbe:Cbei_2898 histidine kinase internal region; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.909
ADK81757.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR010559:IPR003594; KEGG: cpy:Cphy_3281 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.895
ADK81185.1
Signal transduction histidine kinase, LytS; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR004358:IPR005467:IPR010559:IPR003594; KEGG: cpy:Cphy_3281 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SPTR: Putative two-component sensor kinase YesM; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.893
ADK82501.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594:IPR005467; KEGG: cbe:Cbei_1382 histidine kinase internal region; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: Histidine kinase internal region; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.886
ADK79765.1
Histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: csc:Csac_2551 integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.878
ADK82513.1
Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR005479; KEGG: sro:Sros_6223 periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: family.
 
     0.840
ADK83156.1
Signal transduction histidine kinase, LytS; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR003660:IPR010559:IPR003594; KEGG: tit:Thit_0243 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: Histidine kinase family protein; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
  
 0.760
ADK82507.1
Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: cce:Ccel_1226 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Monosaccharide-transporting ATPase; PFAM: Branched-chain amino acid transport system / permease component.
 
    0.731
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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