STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK82723.1Metallophosphoesterase; InterPro IPR004843:IPR010916:IPR011152; KEGG: rrs:RoseRS_4037 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family. (263 aa)    
Predicted Functional Partners:
ADK80416.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.842
ADK82724.1
COGs: COG2365 Protein tyrosine/serine phosphatase; KEGG: apr:Apre_0673 protein tyrosine/serine phosphatase; SPTR: Protein tyrosine/serine phosphatase.
   
   0.791
ADK79483.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
 
 0.578
ADK82172.1
Peptidase C14 caspase catalytic subunit p20; COGs: COG0666 FOG: Ankyrin repeat; InterProIPR002110:IPR003646:IPR020683:IPR010466:IPR 011600:IPR018247:IPR001917; KEGG: sit:TM1040_0843 OmpA/MotB; PFAM: peptidase C14 caspase catalytic subunit p20; Ankyrin; protein of unknown function DUF1058; SMART: SH3 domain protein; Ankyrin; SPTR: Putative uncharacterized protein; PFAM: Caspase domain; Bacterial SH3 domain; Ankyrin repeat.
   
 
 0.509
ADK79363.1
Ankyrin; InterPro IPR002110:IPR020683; KEGG: afv:AFLA_025240 ankyrin repeat-containing protein, putative; PFAM: Ankyrin; SMART: Ankyrin; SPTR: Ankyrin repeat-containing protein, putative; PFAM: Ankyrin repeat.
    
 
 0.496
ADK80620.1
Ankyrin; InterPro IPR002110:IPR020683; KEGG: tde:TDE2450 ankyrin repeateat-containing protein; SMART: Ankyrin; SPTR: Ankyrin repeat protein; PFAM: Ankyrin repeat.
    
 
 0.496
ADK81641.1
KEGG: nhl:Nhal_1282 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 
 0.496
ADK79285.1
COGs: COG0627 esterase; InterPro IPR000801; KEGG: bbe:BBR47_31170 hypothetical protein; PFAM: putative esterase; SPTR: Putative uncharacterized protein; PFAM: Putative esterase.
  
  
 0.436
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.