STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK82800.1Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018488:IPR000595:IPR002373; KEGG: mxa:MXAN_2702 cyclic nucleotide-binding domain-containing protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding domain protein; PFAM: Cyclic nucleotide-binding domain. (209 aa)    
Predicted Functional Partners:
ADK82213.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR002373:IPR018488; KEGG: tde:TDE2437 cyclic nucleotide binding domain-containing protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide binding domain protein; PFAM: Cyclic nucleotide-binding domain.
  
  
 
0.924
ADK80864.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR002373:IPR000595:IPR018488; KEGG: tde:TDE2616 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
  
 
0.922
ADK82884.1
Adenylate/guanylate cyclase with Chase sensor; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001901:IPR001054:IPR007890; KEGG: tde:TDE0932 adenylate/guanylate cyclase catalytic domain-containing protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase catalytic domain protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain.
 
 0.835
ADK81181.1
Adenylate/guanylate cyclase with Chase sensor; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: lic:LIC10862 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain.
 
 0.832
ADK79366.1
COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR018370; KEGG: amc:MADE_00483 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain.
 
 0.831
ADK79437.1
COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR001054; KEGG: scl:sce7616 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; PAS domain containing protein; SPTR: Adenylate cyclase; TIGRFAM: PAS sensor protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; TIGRFAM: PAS domain S-box.
 
 0.819
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.621
ADK82801.1
KEGG: mxa:MXAN_5455 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.575
ADK82280.1
KEGG: lbf:LBF_2563 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 0.527
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.519
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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