STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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[Homology]
Score
ADK82895.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR005829:IPR001789:IPR001867; KEGG: csc:Csac_2559 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (227 aa)    
Predicted Functional Partners:
ADK82894.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR005467:IPR 004358; KEGG: bpf:BpOF4_20474 two component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.967
ADK82628.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013656:IPR013655:IPR004358:IPR005467; KEGG: lbf:LBF_0869 sensor histidine kinase and response regulator of a two component complex; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: [...]
 
 
 0.894
ADK81346.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR000014:IPR003661:IPR003594:IPR 013767:IPR005467; KEGG: cpo:COPRO5265_0030 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFA [...]
 
 
 0.871
ADK81864.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: rrs:RoseRS_3736 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.867
ADK80913.1
COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR004358:IPR013767:IPR003661:IPR 003594:IPR005467:IPR003660; KEGG: amt:Amet_3086 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.864
ADK80377.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003661:IPR003594:IPR005467; KEGG: aba:Acid345_3062 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.862
ADK81803.1
Histidine kinase; COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR005467:IPR004358; KEGG: ctc:CTC00873 sensory transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.859
ADK81226.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003660:IPR003661:IPR003594:IPR 005467; KEGG: cpy:Cphy_1862 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosph [...]
 
 0.854
ADK79624.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR004358:IPR013767:IPR008207:IPR005467:IPR000700; KEGG: dma:DMR_25470 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Sensor protein; TIGRFAM: PAS [...]
 
 
0.852
ADK83212.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR008207:IPR 000014:IPR005467:IPR000700:IPR004358; KEGG: dal:Dalk_3917 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regu [...]
 
 
 0.850
Your Current Organism:
Sediminispirochaeta smaragdinae
NCBI taxonomy Id: 573413
Other names: S. smaragdinae DSM 11293, Sediminispirochaeta smaragdinae DSM 11293, Spirochaeta smaragdinae DSM 11293
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