node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADK81742.1 | ADK83090.1 | Spirs_2633 | Spirs_4005 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001455:IPR013027:IPR004099:IPR001763; KEGG: pdi:BDI_0541 pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA family protein; SMART: Rhodanese domain protein; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreduct [...] | PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR000014:IPR005467:IPR000700:IPR004358; KEGG: dvl:Dvul_0331 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: P [...] | 0.464 |
ADK81742.1 | ADK83093.1 | Spirs_2633 | Spirs_4008 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001455:IPR013027:IPR004099:IPR001763; KEGG: pdi:BDI_0541 pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA family protein; SMART: Rhodanese domain protein; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreduct [...] | LemA family protein; COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: tex:Teth514_0283 LemA family protein; PFAM: LemA family protein; SPTR: LemA family protein; PFAM: LemA family. | 0.418 |
ADK83087.1 | ADK83088.1 | Spirs_4002 | Spirs_4003 | COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: pseudouridylate synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase. | COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: Topoisomerase IV, A subunit, putative; PFAM: DNA gyrase/topoisomerase IV, subunit A. | 0.837 |
ADK83087.1 | ADK83089.1 | Spirs_4002 | Spirs_4004 | COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: pseudouridylate synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase. | COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241:IPR000565; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; SPTR: DNA topoisomerase 4 subunit B; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus. | 0.852 |
ADK83087.1 | ADK83090.1 | Spirs_4002 | Spirs_4005 | COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: pseudouridylate synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase. | PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR000014:IPR005467:IPR000700:IPR004358; KEGG: dvl:Dvul_0331 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: P [...] | 0.694 |
ADK83087.1 | ADK83091.1 | Spirs_4002 | Spirs_4006 | COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: pseudouridylate synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase. | Hypothetical protein; KEGG: sat:SYN_00536 putative cytoplasmic protein; SPTR: Hypothetical cytosolic protein; PFAM: Nucleotidyltransferase domain. | 0.452 |
ADK83087.1 | ADK83092.1 | Spirs_4002 | Spirs_4007 | COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: pseudouridylate synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase. | Protein of unknown function DUF477; COGs: COG1512 Beta-propeller domains of methanol dehydrogenase type; InterPro IPR007621; KEGG: sat:SYN_00537 beta-propeller domain-containing protein; PFAM: protein of unknown function DUF477; SPTR: Beta-propeller domain of methanol dehydrogenase type protein; PFAM: Domain of unknown function (DUF477). | 0.471 |
ADK83087.1 | ADK83093.1 | Spirs_4002 | Spirs_4008 | COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: pseudouridylate synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase. | LemA family protein; COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: tex:Teth514_0283 LemA family protein; PFAM: LemA family protein; SPTR: LemA family protein; PFAM: LemA family. | 0.424 |
ADK83088.1 | ADK83087.1 | Spirs_4003 | Spirs_4002 | COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: Topoisomerase IV, A subunit, putative; PFAM: DNA gyrase/topoisomerase IV, subunit A. | COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: pseudouridylate synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase. | 0.837 |
ADK83088.1 | ADK83089.1 | Spirs_4003 | Spirs_4004 | COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: Topoisomerase IV, A subunit, putative; PFAM: DNA gyrase/topoisomerase IV, subunit A. | COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241:IPR000565; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; SPTR: DNA topoisomerase 4 subunit B; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus. | 0.998 |
ADK83088.1 | ADK83090.1 | Spirs_4003 | Spirs_4005 | COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: Topoisomerase IV, A subunit, putative; PFAM: DNA gyrase/topoisomerase IV, subunit A. | PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR000014:IPR005467:IPR000700:IPR004358; KEGG: dvl:Dvul_0331 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: P [...] | 0.727 |
ADK83088.1 | ADK83091.1 | Spirs_4003 | Spirs_4006 | COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: Topoisomerase IV, A subunit, putative; PFAM: DNA gyrase/topoisomerase IV, subunit A. | Hypothetical protein; KEGG: sat:SYN_00536 putative cytoplasmic protein; SPTR: Hypothetical cytosolic protein; PFAM: Nucleotidyltransferase domain. | 0.482 |
ADK83088.1 | ADK83092.1 | Spirs_4003 | Spirs_4007 | COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: Topoisomerase IV, A subunit, putative; PFAM: DNA gyrase/topoisomerase IV, subunit A. | Protein of unknown function DUF477; COGs: COG1512 Beta-propeller domains of methanol dehydrogenase type; InterPro IPR007621; KEGG: sat:SYN_00537 beta-propeller domain-containing protein; PFAM: protein of unknown function DUF477; SPTR: Beta-propeller domain of methanol dehydrogenase type protein; PFAM: Domain of unknown function (DUF477). | 0.457 |
ADK83088.1 | ADK83093.1 | Spirs_4003 | Spirs_4008 | COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: Topoisomerase IV, A subunit, putative; PFAM: DNA gyrase/topoisomerase IV, subunit A. | LemA family protein; COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: tex:Teth514_0283 LemA family protein; PFAM: LemA family protein; SPTR: LemA family protein; PFAM: LemA family. | 0.428 |
ADK83089.1 | ADK83087.1 | Spirs_4004 | Spirs_4002 | COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241:IPR000565; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; SPTR: DNA topoisomerase 4 subunit B; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus. | COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: pseudouridylate synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase. | 0.852 |
ADK83089.1 | ADK83088.1 | Spirs_4004 | Spirs_4003 | COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241:IPR000565; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; SPTR: DNA topoisomerase 4 subunit B; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus. | COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: Topoisomerase IV, A subunit, putative; PFAM: DNA gyrase/topoisomerase IV, subunit A. | 0.998 |
ADK83089.1 | ADK83090.1 | Spirs_4004 | Spirs_4005 | COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241:IPR000565; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; SPTR: DNA topoisomerase 4 subunit B; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus. | PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR000014:IPR005467:IPR000700:IPR004358; KEGG: dvl:Dvul_0331 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: P [...] | 0.727 |
ADK83089.1 | ADK83091.1 | Spirs_4004 | Spirs_4006 | COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241:IPR000565; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; SPTR: DNA topoisomerase 4 subunit B; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus. | Hypothetical protein; KEGG: sat:SYN_00536 putative cytoplasmic protein; SPTR: Hypothetical cytosolic protein; PFAM: Nucleotidyltransferase domain. | 0.472 |
ADK83089.1 | ADK83092.1 | Spirs_4004 | Spirs_4007 | COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241:IPR000565; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; SPTR: DNA topoisomerase 4 subunit B; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus. | Protein of unknown function DUF477; COGs: COG1512 Beta-propeller domains of methanol dehydrogenase type; InterPro IPR007621; KEGG: sat:SYN_00537 beta-propeller domain-containing protein; PFAM: protein of unknown function DUF477; SPTR: Beta-propeller domain of methanol dehydrogenase type protein; PFAM: Domain of unknown function (DUF477). | 0.452 |
ADK83089.1 | ADK83093.1 | Spirs_4004 | Spirs_4008 | COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241:IPR000565; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; SPTR: DNA topoisomerase 4 subunit B; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus. | LemA family protein; COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: tex:Teth514_0283 LemA family protein; PFAM: LemA family protein; SPTR: LemA family protein; PFAM: LemA family. | 0.437 |