STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SI65_06849DNA polymerase gamma, mitochondrial. (1145 aa)    
Predicted Functional Partners:
SI65_03087
Glycine--tRNA ligase 1, mitochondrial.
   
 
 0.926
SI65_05116
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.767
SI65_00321
AAA_23 domain-containing protein.
  
 
 0.718
SI65_00255
FPG_CAT domain-containing protein.
  
  
 0.699
SI65_02986
Poly [ADP-ribose] polymerase.
     
 0.694
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.662
SI65_05027
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 
 0.651
SI65_08922
Triosephosphate isomerase.
    
 0.649
SI65_03006
Uncharacterized protein.
     
 0.640
SI65_01241
RNase H domain-containing protein.
    
 0.639
Your Current Organism:
Aspergillus cristatus
NCBI taxonomy Id: 573508
Other names: A. cristatus, ATCC 16468, Aspergillus cristatellus, CBS 123.53, Eurotium cristatum, IMI 172278, IMI 172280, NRRL 4222
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