STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYCTH_2294092Uncharacterized protein. (80 aa)    
Predicted Functional Partners:
MYCTH_2302247
3'-5' exonuclease domain-containing protein.
   
 0.969
MYCTH_2058328
RING-type domain-containing protein.
    
 0.964
MYCTH_2126860
DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.
    
 0.964
MYCTH_2296782
AAA domain-containing protein.
   
 0.936
MYCTH_63866
Uncharacterized protein.
   
 0.935
MYCTH_2313161
AAA domain-containing protein.
   
 0.879
MYCTH_2300696
AAA domain-containing protein.
   
 0.860
MYCTH_2312770
AAA domain-containing protein.
   
 0.850
MYCTH_115624
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.798
MYCTH_92074
Phosphatidyl inositol 3-kinase-like protein; Belongs to the PI3/PI4-kinase family.
    
 0.770
Your Current Organism:
Thermothelomyces thermophilus
NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.