STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYCTH_2050514Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (368 aa)    
Predicted Functional Partners:
MYCTH_39317
AAA_23 domain-containing protein.
   
 0.999
MYCTH_2306463
SP-RING-type domain-containing protein.
    
 0.999
MYCTH_2309195
SMC_N domain-containing protein.
   
 0.999
MYCTH_112716
zf-RING-like domain-containing protein.
   
 0.999
MYCTH_2298143
MAGE domain-containing protein.
   
 0.998
MYCTH_2314727
Chalcone_isomerase domain-containing protein.
   
 0.964
MYCTH_2304799
Structural maintenance of chromosomes protein.
   
 0.889
MYCTH_2300741
Structural maintenance of chromosomes protein.
   
 0.838
MYCTH_2303908
Uncharacterized protein.
   
 0.838
MYCTH_73867
Structural maintenance of chromosomes protein.
   
 0.779
Your Current Organism:
Thermothelomyces thermophilus
NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464
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