STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYCTH_2299349Uncharacterized protein. (764 aa)    
Predicted Functional Partners:
MYCTH_109978
Pyruvate carboxyltransferase-like protein.
  
 
 0.989
MYCTH_2304102
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.988
MYCTH_2085059
ACT domain-containing protein.
  
  
 0.928
MYCTH_2307131
Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.847
MYCTH_2065465
Uncharacterized protein.
  
 
 0.847
MYCTH_2071098
Uncharacterized protein.
  
 
 0.847
MYCTH_110317
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.842
MYCTH_38939
Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.842
MYCTH_2312869
Pyruvate carboxyltransferase domain-containing protein.
  
 
 0.838
MYCTH_2066697
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.827
Your Current Organism:
Thermothelomyces thermophilus
NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464
Server load: low (16%) [HD]