STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYCTH_2299597Acetolactate synthase. (695 aa)    
Predicted Functional Partners:
MYCTH_2085059
ACT domain-containing protein.
 
 0.999
MYCTH_2133056
Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.
  
 
 0.986
MYCTH_2309088
Threonine dehydratase.
  
 0.975
MYCTH_2304102
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.967
MYCTH_2302253
PALP domain-containing protein.
  
 0.962
MYCTH_109978
Pyruvate carboxyltransferase-like protein.
  
 
 0.921
MYCTH_2297263
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.905
MYCTH_2302433
Uncharacterized protein.
  
 
 0.903
MYCTH_2307908
Malic enzyme.
  
 
 0.903
MYCTH_2066697
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.895
Your Current Organism:
Thermothelomyces thermophilus
NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464
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