STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYCTH_2306252BRCT domain-containing protein. (1062 aa)    
Predicted Functional Partners:
MYCTH_2093728
Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
   
 0.966
MYCTH_2307601
Uncharacterized protein.
   
 0.849
MYCTH_2308296
MPN domain-containing protein.
    
 0.841
MYCTH_2306355
Uncharacterized protein.
    
 0.797
MYCTH_2074077
RRN7-type domain-containing protein.
    
  0.783
MYCTH_2295647
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.756
MYCTH_2063758
Uncharacterized protein.
     
 0.749
MYCTH_2294499
Uncharacterized protein.
   
 0.746
MYCTH_2109793
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
     
 0.721
MYCTH_2306730
BZIP domain-containing protein.
   
 0.661
Your Current Organism:
Thermothelomyces thermophilus
NCBI taxonomy Id: 573729
Other names: Myceliophthora thermophila ATCC 42464, Sporotrichum thermophile ATCC 42464, T. thermophilus ATCC 42464, Thermothelomyces thermophilus ATCC 42464, Thielavia heterothallica ATCC 42464
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