STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADL12381.1GHMP kinase; COGs: COG4542 Protein involved in propanediol utilization and related protein (includes coumermycin biosynthetic protein) possible kinase; InterPro IPR012363:IPR006204:IPR013750:IPR020568; KEGG: mta:Moth_1103 GHMP kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: A1HPW0 GHMP kinase; PFAM: GHMP kinases N terminal domain. (302 aa)    
Predicted Functional Partners:
ADL12371.1
COGs: COG2073 Cobalamin biosynthesis protein CbiG; InterPro IPR002750; KEGG: drm:Dred_2710 cobalamin (vitamin B12) biosynthesis CbiG protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; SPTR: A1HPX3 Cobalamin (Vitamin B12) biosynthesis CbiG protein; PFAM: Cobalamin biosynthesis central region; Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal.
 
  
 0.987
ADL12382.1
L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR004838:IPR001176:IPR015421:IPR015422:IPR 004839:IPR015424:IPR005860; KEGG: dae:Dtox_3089 L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: C1TJJ7 L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase.
  
 
 0.984
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.890
ADL12383.1
COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR001345:IPR013078:IPR017578; KEGG: mta:Moth_1105 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Q2RJH0 Phosphoglycerate mutase; TIGRFAM: alpha-ribazole phosphatase; PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase.
 
  
 0.869
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
  
 0.847
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 0.829
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
     
 0.822
ADL12372.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR014777:IPR000878:IPR006363; KEGG: dps:DP0224 precorrin-3B C17-methyltransferase (CobJ); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Q6ARS2 Probable precorrin-3B C17-methyltransferase (CobJ); TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase.
  
  
 0.813
ADL12373.1
COGs: COG2099 Precorrin-6x reductase; InterPro IPR003723; KEGG: dae:Dtox_1297 precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; SPTR: C6PHW4 Precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase.
 
  
 0.811
ADL12365.1
precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: cby:CLM_1073 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: C1FVC4 Precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase.
 
    0.809
Your Current Organism:
Acetohalobium arabaticum
NCBI taxonomy Id: 574087
Other names: A. arabaticum DSM 5501, Acetohalobium arabaticum DSM 5501, Acetohalobium arabaticum str. DSM 5501, Acetohalobium arabaticum strain DSM 5501
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