STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL13162.1Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: csc:Csac_2148 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: A4XLE5 UPF0102 protein Csac_2148; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252. (120 aa)    
Predicted Functional Partners:
ADL13161.1
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterProIPR001208:IPR004482:IPR000523:IPR003593:IPR 020568; KEGG: hor:Hore_07410 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: B8CW29 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein.
 
  
 0.948
ADL13160.1
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488:IPR010994; KEGG: hor:Hore_07520 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: B8CW40 DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
    0.866
ADL11793.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: amt:Amet_0723 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: A6TL80 Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
 
    0.715
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.556
ADL13163.1
Conserved hypothetical protein; InterPro IPR009097; KEGG: hor:Hore_02930 hypothetical protein; SPTR: B8D1H7 Putative uncharacterized protein.
       0.515
ADL12394.1
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR000644:IPR000160; KEGG: hmo:HM1_2081 signal transduction protein, putative; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: B0TGE2 Signal transduction protein, putative; PFAM: EAL domain; CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
   
    0.473
codY
GTP-sensing pleiotropic transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
       0.447
ADL12848.1
Type III secretion exporter; COGs: COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB; InterPro IPR006135; KEGG: hor:Hore_19930 FlhB domain protein; PFAM: type III secretion exporter; SPTR: B3KIA0 Cytoplasmic domain of flagellar protein FhlB-like protein; PFAM: FlhB HrpN YscU SpaS Family; TIGRFAM: flhB C-terminus-related protein.
 
     0.440
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.415
ADL13167.1
COGs: COG0681 Signal peptidase I; InterProIPR000223:IPR011056:IPR019759:IPR019756:IPR 019757:IPR019758:IPR015927; KEGG: dth:DICTH_1422 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: C1TKM4 Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
  
    0.408
Your Current Organism:
Acetohalobium arabaticum
NCBI taxonomy Id: 574087
Other names: A. arabaticum DSM 5501, Acetohalobium arabaticum DSM 5501, Acetohalobium arabaticum str. DSM 5501, Acetohalobium arabaticum strain DSM 5501
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