STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HA38_03345DNA damage-inducible SOS regulon protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)    
Predicted Functional Partners:
sulA
Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
   
    0.869
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
  
 0.815
HA38_21300
DNA polymerase V subunit UmuC; Binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S24 family.
   
  
 0.811
HA38_19780
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.747
HA38_13915
DNA damage-inducible protein I; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.708
HA38_14090
DNA polymerase V; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.698
HA38_07235
Flagellar protein FlhE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.671
rraB
Ornithine carbamoyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.590
HA38_02790
Lipoprotein NlpI; May be involved in cell division.
  
     0.558
HA38_03350
Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.553
Your Current Organism:
Pantoea allii
NCBI taxonomy Id: 574096
Other names: LMG 24248, LMG:24248, P. allii, Pantoea allii Brady et al. 2011, Pantoea sp. BD380, Pantoea sp. BD381, Pantoea sp. BD383, Pantoea sp. BD391, Pantoea sp. BD392, strain BD 390
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.