| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HA38_01690 | HA38_18760 | HA38_01690 | HA38_18760 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | 0.411 |
| HA38_01690 | mtnA | HA38_01690 | HA38_23105 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.881 |
| HA38_01690 | mtnB | HA38_01690 | HA38_20780 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.584 |
| HA38_01690 | mtnK | HA38_01690 | HA38_23100 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.789 |
| HA38_01690 | mtnN | HA38_01690 | HA38_14735 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Vitamin B12 ABC transporter substrate-binding protein BtuF; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulatio [...] | 0.603 |
| HA38_18440 | HA38_23190 | HA38_18440 | HA38_23190 | 5'-nucleotidase, lipoprotein e(P4) family; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.937 |
| HA38_18440 | mtnA | HA38_18440 | HA38_23105 | 5'-nucleotidase, lipoprotein e(P4) family; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.914 |
| HA38_18440 | mtnK | HA38_18440 | HA38_23100 | 5'-nucleotidase, lipoprotein e(P4) family; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.912 |
| HA38_18440 | mtnN | HA38_18440 | HA38_14735 | 5'-nucleotidase, lipoprotein e(P4) family; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Vitamin B12 ABC transporter substrate-binding protein BtuF; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulatio [...] | 0.915 |
| HA38_18760 | HA38_01690 | HA38_18760 | HA38_01690 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.411 |
| HA38_18760 | mtnK | HA38_18760 | HA38_23100 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.534 |
| HA38_18760 | mtnN | HA38_18760 | HA38_14735 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | Vitamin B12 ABC transporter substrate-binding protein BtuF; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulatio [...] | 0.483 |
| HA38_22595 | HA38_22600 | HA38_22595 | HA38_22600 | Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. | Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| HA38_22595 | mtnK | HA38_22595 | HA38_23100 | Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. | S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.600 |
| HA38_22600 | HA38_22595 | HA38_22600 | HA38_22595 | Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. | 0.997 |
| HA38_22600 | mtnA | HA38_22600 | HA38_23105 | Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.825 |
| HA38_22600 | mtnB | HA38_22600 | HA38_20780 | Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.511 |
| HA38_22600 | mtnK | HA38_22600 | HA38_23100 | Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.764 |
| HA38_23190 | HA38_18440 | HA38_23190 | HA38_18440 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | 5'-nucleotidase, lipoprotein e(P4) family; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
| HA38_23190 | mtnA | HA38_23190 | HA38_23105 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.914 |