| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SDW15934.1 | SDW15987.1 | SAMN05443545_101259 | SAMN05443545_101260 | N-acetylmuramoyl-L-alanine amidase. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.871 |
| SDW15934.1 | miaA | SAMN05443545_101259 | SAMN05443545_101257 | N-acetylmuramoyl-L-alanine amidase. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.918 |
| SDW15934.1 | mutL | SAMN05443545_101259 | SAMN05443545_101258 | N-acetylmuramoyl-L-alanine amidase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.900 |
| SDW15934.1 | nnrE | SAMN05443545_101259 | SAMN05443545_101261 | N-acetylmuramoyl-L-alanine amidase. | NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...] | 0.907 |
| SDW15987.1 | SDW15934.1 | SAMN05443545_101260 | SAMN05443545_101259 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | N-acetylmuramoyl-L-alanine amidase. | 0.871 |
| SDW15987.1 | miaA | SAMN05443545_101260 | SAMN05443545_101257 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.880 |
| SDW15987.1 | mutL | SAMN05443545_101260 | SAMN05443545_101258 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.829 |
| SDW15987.1 | nnrE | SAMN05443545_101260 | SAMN05443545_101261 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...] | 0.954 |
| SDW53157.1 | nnrE | SAMN05443545_102105 | SAMN05443545_101261 | NAD-dependent formate dehydrogenase flavoprotein subunit. | NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...] | 0.941 |
| SDX77009.1 | SDY07338.1 | SAMN05443545_10797 | SAMN05443545_11071 | NUDIX domain-containing protein. | ATP-dependent RNA helicase CsdA; Belongs to the DEAD box helicase family. | 0.807 |
| SDX77009.1 | nnrE | SAMN05443545_10797 | SAMN05443545_101261 | NUDIX domain-containing protein. | NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...] | 0.973 |
| SDX77009.1 | rapA | SAMN05443545_10797 | SAMN05443545_11235 | NUDIX domain-containing protein. | ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.845 |
| SDX77009.1 | rhlB | SAMN05443545_10797 | SAMN05443545_10193 | NUDIX domain-containing protein. | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.807 |
| SDY07338.1 | SDX77009.1 | SAMN05443545_11071 | SAMN05443545_10797 | ATP-dependent RNA helicase CsdA; Belongs to the DEAD box helicase family. | NUDIX domain-containing protein. | 0.807 |
| SDY07338.1 | nnrE | SAMN05443545_11071 | SAMN05443545_101261 | ATP-dependent RNA helicase CsdA; Belongs to the DEAD box helicase family. | NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...] | 0.954 |
| SDY07338.1 | rapA | SAMN05443545_11071 | SAMN05443545_11235 | ATP-dependent RNA helicase CsdA; Belongs to the DEAD box helicase family. | ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.648 |
| SDY07338.1 | rppH | SAMN05443545_11071 | SAMN05443545_101405 | ATP-dependent RNA helicase CsdA; Belongs to the DEAD box helicase family. | Putative (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.819 |
| miaA | SDW15934.1 | SAMN05443545_101257 | SAMN05443545_101259 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | N-acetylmuramoyl-L-alanine amidase. | 0.918 |
| miaA | SDW15987.1 | SAMN05443545_101257 | SAMN05443545_101260 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.880 |
| miaA | mutL | SAMN05443545_101257 | SAMN05443545_101258 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.954 |
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