| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SDW90580.1 | ubiA | SAMN05443545_103165 | SAMN05443545_103167 | rubredoxin-NAD+ reductase; Belongs to the FAD-dependent oxidoreductase family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.507 |
| SDW90580.1 | ubiC | SAMN05443545_103165 | SAMN05443545_103166 | rubredoxin-NAD+ reductase; Belongs to the FAD-dependent oxidoreductase family. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.663 |
| SDW90777.1 | ubiA | SAMN05443545_103169 | SAMN05443545_103167 | PAS/PAC sensor signal transduction histidine kinase. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.614 |
| SDW90777.1 | ubiC | SAMN05443545_103169 | SAMN05443545_103166 | PAS/PAC sensor signal transduction histidine kinase. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.575 |
| SDX00899.1 | ubiC | SAMN05443545_103385 | SAMN05443545_103166 | HemY protein. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.517 |
| SDX32360.1 | SDY10798.1 | SAMN05443545_10510 | SAMN05443545_11125 | Chorismate mutase. | Anthranilate synthase, component II. | 0.944 |
| SDX32360.1 | aroA | SAMN05443545_10510 | SAMN05443545_10511 | Chorismate mutase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.999 |
| SDX32360.1 | trpD | SAMN05443545_10510 | SAMN05443545_11126 | Chorismate mutase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.932 |
| SDX32360.1 | trpE | SAMN05443545_10510 | SAMN05443545_11123 | Chorismate mutase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.942 |
| SDX32360.1 | ubiC | SAMN05443545_10510 | SAMN05443545_103166 | Chorismate mutase. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.906 |
| SDX44122.1 | ubiA | SAMN05443545_105293 | SAMN05443545_103167 | 4-hydroxybenzoyl-CoA thioesterase/acyl-CoA thioester hydrolase. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.837 |
| SDX44122.1 | ubiC | SAMN05443545_105293 | SAMN05443545_103166 | 4-hydroxybenzoyl-CoA thioesterase/acyl-CoA thioester hydrolase. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.834 |
| SDY10798.1 | SDX32360.1 | SAMN05443545_11125 | SAMN05443545_10510 | Anthranilate synthase, component II. | Chorismate mutase. | 0.944 |
| SDY10798.1 | aroA | SAMN05443545_11125 | SAMN05443545_10511 | Anthranilate synthase, component II. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.806 |
| SDY10798.1 | trpD | SAMN05443545_11125 | SAMN05443545_11126 | Anthranilate synthase, component II. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
| SDY10798.1 | trpE | SAMN05443545_11125 | SAMN05443545_11123 | Anthranilate synthase, component II. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.999 |
| SDY10798.1 | ubiC | SAMN05443545_11125 | SAMN05443545_103166 | Anthranilate synthase, component II. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.850 |
| aroA | SDX32360.1 | SAMN05443545_10511 | SAMN05443545_10510 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate mutase. | 0.999 |
| aroA | SDY10798.1 | SAMN05443545_10511 | SAMN05443545_11125 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase, component II. | 0.806 |
| aroA | trpD | SAMN05443545_10511 | SAMN05443545_11126 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.790 |
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