node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDX34603.1 | SDX34671.1 | SAMN05443545_10565 | SAMN05443545_10567 | Membrane-bound lytic murein transglycosylase B. | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | 0.694 |
SDX34603.1 | SDX34712.1 | SAMN05443545_10565 | SAMN05443545_10568 | Membrane-bound lytic murein transglycosylase B. | Hypothetical protein; Belongs to the UPF0250 family. | 0.487 |
SDX34603.1 | mrdA | SAMN05443545_10565 | SAMN05443545_10563 | Membrane-bound lytic murein transglycosylase B. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.828 |
SDX34603.1 | mrdB | SAMN05443545_10565 | SAMN05443545_10564 | Membrane-bound lytic murein transglycosylase B. | Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.761 |
SDX34603.1 | nadD | SAMN05443545_10565 | SAMN05443545_10560 | Membrane-bound lytic murein transglycosylase B. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.508 |
SDX34603.1 | proA | SAMN05443545_10565 | SAMN05443545_10559 | Membrane-bound lytic murein transglycosylase B. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.508 |
SDX34603.1 | rlmH | SAMN05443545_10565 | SAMN05443545_10562 | Membrane-bound lytic murein transglycosylase B. | 23S rRNA (pseudouridine1915-N3)-methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.605 |
SDX34603.1 | rlpA-2 | SAMN05443545_10565 | SAMN05443545_10566 | Membrane-bound lytic murein transglycosylase B. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.859 |
SDX34603.1 | rsfS | SAMN05443545_10565 | SAMN05443545_10561 | Membrane-bound lytic murein transglycosylase B. | Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.564 |
SDX34603.1 | secB | SAMN05443545_10565 | SAMN05443545_103290 | Membrane-bound lytic murein transglycosylase B. | Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.616 |
SDX34671.1 | SDX34603.1 | SAMN05443545_10567 | SAMN05443545_10565 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | Membrane-bound lytic murein transglycosylase B. | 0.694 |
SDX34671.1 | SDX34712.1 | SAMN05443545_10567 | SAMN05443545_10568 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | Hypothetical protein; Belongs to the UPF0250 family. | 0.621 |
SDX34671.1 | mrdA | SAMN05443545_10567 | SAMN05443545_10563 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.949 |
SDX34671.1 | mrdB | SAMN05443545_10567 | SAMN05443545_10564 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.688 |
SDX34671.1 | rlmH | SAMN05443545_10567 | SAMN05443545_10562 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | 23S rRNA (pseudouridine1915-N3)-methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.594 |
SDX34671.1 | rlpA-2 | SAMN05443545_10567 | SAMN05443545_10566 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.621 |
SDX34671.1 | rsfS | SAMN05443545_10567 | SAMN05443545_10561 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.441 |
SDX34671.1 | secB | SAMN05443545_10567 | SAMN05443545_103290 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.513 |
SDX34712.1 | SDX34603.1 | SAMN05443545_10568 | SAMN05443545_10565 | Hypothetical protein; Belongs to the UPF0250 family. | Membrane-bound lytic murein transglycosylase B. | 0.487 |
SDX34712.1 | SDX34671.1 | SAMN05443545_10568 | SAMN05443545_10567 | Hypothetical protein; Belongs to the UPF0250 family. | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family. | 0.621 |