| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SDW52470.1 | SDX42520.1 | SAMN05443545_10293 | SAMN05443545_105255 | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.878 |
| SDW52470.1 | SDY06372.1 | SAMN05443545_10293 | SAMN05443545_11046 | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | Methyltransferase domain-containing protein. | 0.477 |
| SDW52470.1 | gcvP | SAMN05443545_10293 | SAMN05443545_105340 | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.998 |
| SDW52470.1 | ubiG | SAMN05443545_10293 | SAMN05443545_105284 | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.546 |
| SDX42520.1 | SDW52470.1 | SAMN05443545_105255 | SAMN05443545_10293 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.878 |
| SDX42520.1 | SDY06372.1 | SAMN05443545_105255 | SAMN05443545_11046 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methyltransferase domain-containing protein. | 0.421 |
| SDX42520.1 | bioB | SAMN05443545_105255 | SAMN05443545_10537 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.430 |
| SDX42520.1 | gcvP | SAMN05443545_105255 | SAMN05443545_105340 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.620 |
| SDX58978.1 | SDY06372.1 | SAMN05443545_106137 | SAMN05443545_11046 | Cytochrome P450. | Methyltransferase domain-containing protein. | 0.434 |
| SDY06335.1 | SDY06372.1 | SAMN05443545_11045 | SAMN05443545_11046 | Uncharacterized conserved protein. | Methyltransferase domain-containing protein. | 0.644 |
| SDY06372.1 | SDW52470.1 | SAMN05443545_11046 | SAMN05443545_10293 | Methyltransferase domain-containing protein. | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.477 |
| SDY06372.1 | SDX42520.1 | SAMN05443545_11046 | SAMN05443545_105255 | Methyltransferase domain-containing protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.421 |
| SDY06372.1 | SDX58978.1 | SAMN05443545_11046 | SAMN05443545_106137 | Methyltransferase domain-containing protein. | Cytochrome P450. | 0.434 |
| SDY06372.1 | SDY06335.1 | SAMN05443545_11046 | SAMN05443545_11045 | Methyltransferase domain-containing protein. | Uncharacterized conserved protein. | 0.644 |
| SDY06372.1 | bioB | SAMN05443545_11046 | SAMN05443545_10537 | Methyltransferase domain-containing protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.424 |
| SDY06372.1 | gcvP | SAMN05443545_11046 | SAMN05443545_105340 | Methyltransferase domain-containing protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.591 |
| SDY06372.1 | ubiG | SAMN05443545_11046 | SAMN05443545_105284 | Methyltransferase domain-containing protein. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.468 |
| bioB | SDX42520.1 | SAMN05443545_10537 | SAMN05443545_105255 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.430 |
| bioB | SDY06372.1 | SAMN05443545_10537 | SAMN05443545_11046 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Methyltransferase domain-containing protein. | 0.424 |
| bioB | gcvP | SAMN05443545_10537 | SAMN05443545_105340 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.414 |
STRING v12.5 is now available!
