STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
BAMA_05035acetyl-CoA synthetase; Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)    
Predicted Functional Partners:
BAMA_05040
Acetoin dehydrogenase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue.
 
 
 0.988
eutD
Phosphotransacetylase; In Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.957
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.949
BAMA_08240
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.910
BAMA_06340
Citrate synthase 3; Forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle, glyoxylate cycle and respiration; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 0.900
BAMA_06350
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
  
 
 0.889
BAMA_02395
Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.876
BAMA_17110
Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family.
   
 0.874
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.868
BAMA_05050
Histone deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.866
Your Current Organism:
Bacillus manliponensis
NCBI taxonomy Id: 574376
Other names: B. manliponensis, Bacillus sp. BL4-6, JCM 15802, KCTC 13319, strain BL4-6
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