Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BAMA_07775PemK family transcriptional regulator; Toxic component of a type II toxin-antitoxin (TA) system. (116 aa)    
Predicted Functional Partners:
BAMA_07770
Antitoxin endoai; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.993
gyrB
DNA gyrase subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
      
 0.582
BAMA_07780
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.578
BAMA_11660
CtsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CtsR family.
  
     0.555
gpsB
Cell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
    0.531
BAMA_07765
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.485
BAMA_00365
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.477
BAMA_00885
HxlR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.477
BAMA_05470
Regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.477
BAMA_17680
HxlR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.477
Your Current Organism:
Bacillus manliponensis
NCBI taxonomy Id: 574376
Other names: B. manliponensis, Bacillus sp. BL4-6, JCM 15802, KCTC 13319, strain BL4-6
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