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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa)    
Predicted Functional Partners:
BAMA_08090
3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.998
BAMA_00625
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.827
BAMA_00630
Pyridoxal-5'-phosphate-dependent protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.827
BAMA_08095
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.805
BAMA_01795
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.763
BAMA_18335
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.763
BAMA_18340
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.742
pheA
Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.740
mnmE
tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
    
 0.732
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.672
Your Current Organism:
Bacillus manliponensis
NCBI taxonomy Id: 574376
Other names: B. manliponensis, Bacillus sp. BL4-6, JCM 15802, KCTC 13319, strain BL4-6
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