STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACIS_00541Hypothetical protein. (388 aa)    
Predicted Functional Partners:
oma87
Outer membrane protein/protective antigen OMA87; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
 
 0.996
bamD
Putative DNA uptake lipoprotein ComL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
 
 0.942
ACIS_00053
Hypothetical protein.
  
 
 0.895
lpdA
Dihydrolipoamide dehydrogenase.
  
    0.820
ACIS_00544
Contains conserved domain COG0845: membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
     0.820
ACIS_00646
Hypothetical protein.
    
 
 0.722
ACIS_00790
Contains conserved domain PRK10788: peptidyl-prolyl cis-trans isomerase (rotamase D).
  
 
 0.601
der
GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.586
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
       0.576
maf
Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.576
Your Current Organism:
Anaplasma centrale
NCBI taxonomy Id: 574556
Other names: A. centrale str. Israel, Anaplasma centrale str. Israel, Anaplasma centrale strain Israel, Anaplasma marginale subsp. centrale str. Israel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.