STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACIS_00544Contains conserved domain COG0845: membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (371 aa)    
Predicted Functional Partners:
ACIS_00590
AcrB/AcrD/AcrF family cation efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.984
tolC
Outer membrane protein TolC.
 
 
 0.955
lolD
ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 
 0.859
ACIS_00541
Hypothetical protein.
 
     0.820
lpdA
Dihydrolipoamide dehydrogenase.
       0.816
maf
Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.637
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
       0.636
ACIS_00807
Putative histidine kinase sensor protein.
 
   
 0.559
der
GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
     0.526
ACIS_01052
Putative secretion protein; Contains conserved domain pfam00529: HlyD family secretion protein.
 
  
 0.475
Your Current Organism:
Anaplasma centrale
NCBI taxonomy Id: 574556
Other names: A. centrale str. Israel, Anaplasma centrale str. Israel, Anaplasma centrale strain Israel, Anaplasma marginale subsp. centrale str. Israel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.