STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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Experiments
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[Homology]
Score
ACIS_00837Putative glutamate synthase; Contains conserved domain PRK06567: putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase. (1133 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.999
fdx
Ferredoxin.
  
 0.995
carB
Carbamoyl phosphate synthase large subunit; Belongs to the CarB family.
  
 
 0.988
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
  
 0.988
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.982
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.976
carA
Carbamoyl phosphate synthase small subunit; Belongs to the CarA family.
  
  
 0.944
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.919
fdxA
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
 
 
 0.793
ACIS_00650
Putative cysteine desulfurase; Contains conserved domain COG1104: cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
  
  
 0.642
Your Current Organism:
Anaplasma centrale
NCBI taxonomy Id: 574556
Other names: A. centrale str. Israel, Anaplasma centrale str. Israel, Anaplasma centrale strain Israel, Anaplasma marginale subsp. centrale str. Israel
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