STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I0YQD9_COCSCDNA gyrase, A subunit. (857 aa)    
Predicted Functional Partners:
I0Z5J5_COCSC
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
 
 
 0.889
I0YVC8_COCSC
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
  
 0.798
I0YZE8_COCSC
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.778
I0Z480_COCSC
3-dehydroquinate synthase AroB.
 
    
 0.748
I0YIK0_COCSC
RecF/RecN/SMC protein.
   
 
 0.735
I0Z4Q2_COCSC
Uncharacterized protein.
   
 
 0.664
I0YMD8_COCSC
Structural maintenance of chromosomes protein.
   
 
 0.644
I0Z4J5_COCSC
DNase I-like protein.
      
 0.627
I0Z8U8_COCSC
P-loop containing nucleoside triphosphate hydrolase protein.
   
 
 0.611
I0YU55_COCSC
Ubiquitinating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.610
Your Current Organism:
Coccomyxa subellipsoidea
NCBI taxonomy Id: 574566
Other names: C. subellipsoidea C-169, Chlorella vulgaris C-169, Coccomyxa sp. C-169, Coccomyxa subellipsoidea C-169
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