STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I0YVC8_COCSCBifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. (479 aa)    
Predicted Functional Partners:
I0YNQ0_COCSC
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  
 0.999
I0Z6L2_COCSC
DNA-binding protein.
   
  
 0.999
I0YXG5_COCSC
Thymidine kinase.
  
 
 0.992
I0Z5W2_COCSC
Thymidine kinase.
  
 
 0.992
I0Z7S5_COCSC
Putative Deoxyuridine 5'-triphosphate nucleotidohydrolase.
  
 0.990
I0YT94_COCSC
Methionyl-tRNA formyltransferase.
  
 
 0.987
I0YQ02_COCSC
Thymidylate_kin domain-containing protein.
  
 
 0.982
I0ZA34_COCSC
Formate-tetrahydrofolate ligase.
  
 
 0.982
I0Z0S0_COCSC
Putative phosphoribosylaminoimidazolecarboxamide.
  
 0.979
I0YLA3_COCSC
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.975
Your Current Organism:
Coccomyxa subellipsoidea
NCBI taxonomy Id: 574566
Other names: C. subellipsoidea C-169, Chlorella vulgaris C-169, Coccomyxa sp. C-169, Coccomyxa subellipsoidea C-169
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