I0Z7R6_COCSC protein (Coccomyxa subellipsoidea)

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I0Z7R6_COCSC

ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (513 aa)

Predicted Functional Partners:

I0Z0D2_COCSC

0.984

I0YU24_COCSC

0.836

I0ZA53_COCSC

0.797

I0YND1_COCSC

0.772

I0YVA6_COCSC

0.769

FEN1

0.762

I0Z2B1_COCSC

0.742

I0Z0B8_COCSC

0.739

I0Z559_COCSC

0.738

I0YVU0_COCSC

0.695

Your Current Organism:

Coccomyxa subellipsoidea

NCBI taxonomy Id: 574566
Other names: C. subellipsoidea C-169, Chlorella vulgaris C-169, Coccomyxa sp. C-169, Coccomyxa subellipsoidea C-169

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEN1	I0YND1_COCSC	I0YLG5	I0YND1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DUF1767 domain-containing protein.	0.545
FEN1	I0YU24_COCSC	I0YLG5	I0YU24	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	PIN domain-like protein.	0.854
FEN1	I0YVA6_COCSC	I0YLG5	I0YVA6	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Checkpoint protein; Belongs to the HUS1 family.	0.828
FEN1	I0YVU0_COCSC	I0YLG5	I0YVU0	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.846
FEN1	I0Z0B8_COCSC	I0YLG5	I0Z0B8	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	P-loop containing nucleoside triphosphate hydrolase protein.	0.884
FEN1	I0Z0D2_COCSC	I0YLG5	I0Z0D2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	P-loop containing nucleoside triphosphate hydrolase protein.	0.855
FEN1	I0Z2B1_COCSC	I0YLG5	I0Z2B1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.970
FEN1	I0Z559_COCSC	I0YLG5	I0Z559	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA topoisomerase I.	0.553
FEN1	I0Z7R6_COCSC	I0YLG5	I0Z7R6	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.762
FEN1	I0ZA53_COCSC	I0YLG5	I0ZA53	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.553
I0YND1_COCSC	FEN1	I0YND1	I0YLG5	DUF1767 domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.545
I0YND1_COCSC	I0YU24_COCSC	I0YND1	I0YU24	DUF1767 domain-containing protein.	PIN domain-like protein.	0.851
I0YND1_COCSC	I0YVA6_COCSC	I0YND1	I0YVA6	DUF1767 domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.604
I0YND1_COCSC	I0YVU0_COCSC	I0YND1	I0YVU0	DUF1767 domain-containing protein.	Uncharacterized protein.	0.922
I0YND1_COCSC	I0Z0B8_COCSC	I0YND1	I0Z0B8	DUF1767 domain-containing protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.914
I0YND1_COCSC	I0Z0D2_COCSC	I0YND1	I0Z0D2	DUF1767 domain-containing protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.984
I0YND1_COCSC	I0Z2B1_COCSC	I0YND1	I0Z2B1	DUF1767 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.813
I0YND1_COCSC	I0Z559_COCSC	I0YND1	I0Z559	DUF1767 domain-containing protein.	DNA topoisomerase I.	0.944
I0YND1_COCSC	I0Z7R6_COCSC	I0YND1	I0Z7R6	DUF1767 domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.772
I0YND1_COCSC	I0ZA53_COCSC	I0YND1	I0ZA53	DUF1767 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.944