STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFV24418.1Thiaminase; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. (180 aa)    
Predicted Functional Partners:
SFV20468.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 
 0.894
SFV23372.1
Pyridoxine kinase.
  
 
 0.880
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
 
 0.876
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 
 0.596
SFV24419.1
DNA binding domain-containing protein, excisionase family.
 
     0.549
SFV24420.1
Predicted nucleic acid-binding protein, contains PIN domain.
 
     0.517
SFV24417.1
Uncharacterized conserved protein.
       0.487
SFV20485.1
Bacteriocin biosynthesis cyclodehydratase domain-containing protein.
  
  
 0.451
SFV21917.1
6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase.
  
     0.427
SFV21915.1
Hypothetical protein.
  
     0.412
Your Current Organism:
Micrococcus terreus
NCBI taxonomy Id: 574650
Other names: CGMCC 1.7054, JCM 17489, M. terreus, Micrococcus sp. V3M1, Micrococcus terreus Zhang et al. 2010, NBRC 104258, strain V3M1
Server load: low (28%) [HD]