STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0004Protein of unknown function DUF2088; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: dol:Dole_2523 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088). (475 aa)    
Predicted Functional Partners:
Isop_3494
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: psl:Psta_3844 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: AIR carboxylase.
 
  
 0.872
Isop_1940
Asparagine synthase; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR001962: IPR005232; KEGG: psl:Psta_4402 ExsB family protein; PFAM: asparagine synthase; SPTR: ExsB family protein; manually curated; PFAM: Asparagine synthase; TIGRFAM: conserved hypothetical protein TIGR00268.
 
  
 0.859
Isop_2077
Protein of unknown function DUF111; COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: plm:Plim_2400 protein of unknown function DUF111; PFAM: protein of unknown function DUF111; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF111; TIGRFAM: conserved hypothetical protein TIGR00299; Belongs to the LarC family.
 
  
 0.760
Isop_1424
Cobalamin (vitamin B12) biosynthesis CbiM protein; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: rrs:RoseRS_0174 cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM.
 
    0.546
Isop_2254
KEGG: aba:Acid345_4727 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.437
Isop_0003
Beta-lactamase domain-containing protein; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; InterPro IPR022272; KEGG: afw:Anae109_0563 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
       0.431
Isop_2275
InterPro IPR001623; KEGG: tcu:Tcur_1396 fibronectin type III domain protein; PFAM: heat shock protein DnaJ domain protein; SPTR: Fibronectin type III domain protein.
  
     0.426
Isop_1399
KEGG: rmr:Rmar_0200 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.424
Isop_0706
Protein of unknown function DUF1565; InterPro IPR011506: IPR000209: IPR011459: IPR006626; KEGG: mar:MAE_50880 hypothetical protein; PFAM: protein of unknown function DUF1565; Planctomycete extracellular domain protein; peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Peptidase families S8 and S53 domain protein; PFAM: Protein of unknown function (DUF1565); Subtilase family.
  
     0.418
Isop_2736
KEGG: mxa:MXAN_5625 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.404
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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