STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_0011Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005841: IPR016066: IPR005844: IPR005845; KEGG: rba:RB6061 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; SPTR: Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, al [...] (616 aa)    
Predicted Functional Partners:
Isop_3272
Mannose-6-phosphate isomerase, type 1; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001917: IPR001250: IPR014628; KEGG: psl:Psta_4651 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase, class I; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
 
 
 0.938
Isop_0381
COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835: IPR001538; KEGG: ttr:Tter_0486 mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
  
 
 0.925
Isop_0085
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterProIPR005841: IPR005844: IPR005845: IPR005846: IPR 005843; KEGG: rba:RB9832 phosphomannomutase (pmm); PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphomannomutase (Pmm); PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, [...]
    
 
0.901
Isop_3671
Protein of unknown function DUF147; COGs: COG1624 conserved hypothetical protein; InterPro IPR014499: IPR003390; KEGG: psl:Psta_3542 protein of unknown function DUF147; PFAM: protein of unknown function DUF147; SPTR: Putative uncharacterized protein; PFAM: DisA bacterial checkpoint controller nucleotide-binding.
 
 
 
 0.816
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
  
 0.643
Isop_0131
KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR004800: IPR018506: IPR001347; KEGG: psl:Psta_0845 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein.
  
 
 0.491
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.427
Isop_0012
COGs: COG3380 NAD/FAD-dependent oxidoreductase; InterPro IPR006076; KEGG: caa:Caka_1904 fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD dependent oxidoreductase; SPTR: Putative uncharacterized protein.
       0.421
Isop_0824
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: rrs:RoseRS_4077 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase; PFAM: Nucleotidyl transferase.
  
  
 0.413
Isop_3039
Capsular exopolysaccharide family; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR005702: IPR003856; KEGG: rmr:Rmar_1126 capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein; PRIAM: Non-specific protein-tyrosine kinase; SPTR: Capsular exopolysaccharide family; TIGRFAM: capsular exopolysaccharide family; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family.
  
  
 0.406
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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