STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0020COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR000103: IPR013027: IPR008255; KEGG: acp:A2cp1_4094 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. (345 aa)    
Predicted Functional Partners:
Isop_1968
COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010970; KEGG: ace:Acel_1138 SufS subfamily cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Cysteine desulfurases, SufS subfamily; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily.
 
 
  0.917
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
     
 0.913
Isop_0581
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: rsh:Rsph17029_1561 cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme.
   
 
 0.910
Isop_0702
Thioredoxin domain-containing protein; InterPro IPR013766: IPR017936; KEGG: rba:RB5782 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Probable thioredoxin; PFAM: Thioredoxin.
  
 
 0.828
Isop_2222
Ferredoxin; COGs: COG0633 Ferredoxin; InterPro IPR001055: IPR001041; KEGG: cyt:cce_2108 ferredoxin; PFAM: ferredoxin; SPTR: Probable ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain.
   
 
 0.783
Isop_0459
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR013766: IPR017937: IPR005746: IPR006662: IPR 017936; KEGG: tal:Thal_1357 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
 
 
 0.735
Isop_2248
COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR017937: IPR006662: IPR013766: IPR017936; KEGG: psl:Psta_1606 thioredoxin domain protein; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin domain protein; PFAM: Thioredoxin; TIGRFAM: thioredoxin.
  
 
 0.694
Isop_3719
Hypothetical protein; KEGG: rca:Rcas_0215 TPR repeat-containing protein; SPTR: Tetratricopeptide TPR_2 repeat protein.
  
 
 0.694
Isop_2379
Redoxin domain protein; InterPro IPR017937: IPR013740: IPR000866: IPR017936; KEGG: ote:Oter_0137 redoxin domain-containing protein; PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: AhpC/TSA family.
 
 
 0.583
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
       0.560
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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