STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_0066COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639: IPR000073; KEGG: svi:Svir_29320 predicted hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold; SPTR: Predicted hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold. (273 aa)    
Predicted Functional Partners:
Isop_0067
KEGG: ttr:Tter_2666 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
Isop_2003
KR domain protein; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014031: IPR014043: IPR006163: IPR013968: IPR 009081; KEGG: glo:Glov_2267 polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: KR domain protein; Beta-ketoacyl synthase; Acyl transferase; phosphopantetheine-binding; SPTR: Polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: acyl carrier protein.
  
 0.681
Isop_3434
Metallophosphoesterase; InterPro IPR004843; KEGG: psl:Psta_1609 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase.
    
  0.625
Isop_2245
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: pde:Pden_1042 alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold; SPTR: Alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold.
  
     0.618
Isop_0068
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR019782: IPR017986: IPR006530: IPR 017441: IPR008271: IPR019775: IPR017442: IPR019781: IPR020635:I PR002290: IPR001680; KEGG: psl:Psta_3450 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase; TIGRFAM: YD repeat protein; PFAM: Protein kinase domain; WD domain, G-beta repeat; TIGRFAM: YD repeat (two copies).
   
   0.467
Isop_0069
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007630; KEGG: psl:Psta_2501 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 4 domain protein; SPTR: Probable RNA polymerase sigma-E factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: ECF sigma factor; TIGRFAM: RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1; RNA polymerase sigma factor, sigma-70 family.
       0.463
Isop_2800
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: rmr:Rmar_2446 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: Alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold.
  
     0.441
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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