Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_0070Thioesterase superfamily protein; COGs: COG1607 Acyl-CoA hydrolase; InterPro IPR006683; KEGG: zpr:ZPR_2605 acyl-CoA thioester hydrolase; PFAM: thioesterase superfamily protein; SPTR: Acyl-CoA thioester hydrolase; PFAM: Thioesterase superfamily. (125 aa)    
Predicted Functional Partners:
Isop_0068
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR019782: IPR017986: IPR006530: IPR 017441: IPR008271: IPR019775: IPR017442: IPR019781: IPR020635:I PR002290: IPR001680; KEGG: psl:Psta_3450 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase; TIGRFAM: YD repeat protein; PFAM: Protein kinase domain; WD domain, G-beta repeat; TIGRFAM: YD repeat (two copies).
       0.551
Isop_0069
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007630; KEGG: psl:Psta_2501 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 4 domain protein; SPTR: Probable RNA polymerase sigma-E factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: ECF sigma factor; TIGRFAM: RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1; RNA polymerase sigma factor, sigma-70 family.
       0.551
Isop_1875
COGs: COG2091 Phosphopantetheinyl transferase; InterPro IPR008278; KEGG: ava:Ava_2597 4'-phosphopantetheinyl transferase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: 4'-phosphopantetheinyl transferase; PFAM: 4'-phosphopantetheinyl transferase superfamily; Belongs to the P-Pant transferase superfamily.
   
    0.436
Isop_2372
Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002347; KEGG: plm:Plim_3893 short-chain dehydrogenase/reductase SDR; SPTR: Enoyl-[acyl-carrier-protein] reductase (NADH); PFAM: short chain dehydrogenase.
   
  
 0.435
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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