STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_0085Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterProIPR005841: IPR005844: IPR005845: IPR005846: IPR 005843; KEGG: rba:RB9832 phosphomannomutase (pmm); PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphomannomutase (Pmm); PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, [...] (499 aa)    
Predicted Functional Partners:
Isop_0381
COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835: IPR001538; KEGG: ttr:Tter_0486 mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
 
 
 0.925
Isop_3272
Mannose-6-phosphate isomerase, type 1; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001917: IPR001250: IPR014628; KEGG: psl:Psta_4651 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase, class I; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
  
 
 0.912
Isop_0011
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005841: IPR016066: IPR005844: IPR005845; KEGG: rba:RB6061 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; SPTR: Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, al [...]
    
 
0.901
Isop_3671
Protein of unknown function DUF147; COGs: COG1624 conserved hypothetical protein; InterPro IPR014499: IPR003390; KEGG: psl:Psta_3542 protein of unknown function DUF147; PFAM: protein of unknown function DUF147; SPTR: Putative uncharacterized protein; PFAM: DisA bacterial checkpoint controller nucleotide-binding.
   
 
 0.786
Isop_0084
HAD-superfamily subfamily IB hydrolase, TIGR01490; COGs: COG0560 Phosphoserine phosphatase; InterPro IPR006383: IPR006385: IPR005834; KEGG: hch:HCH_05985 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphoserine phosphatase; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase-like); TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like.
  
    0.783
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
 0.651
Isop_3628
COGs: COG0058 Glucan phosphorylase; InterPro IPR011834: IPR000811; KEGG: psl:Psta_1121 alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: Phosphorylase; SPTR: Alpha-glucan phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases.
  
 
 0.598
Isop_0466
KEGG: plm:Plim_0653 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.587
Isop_2759
COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; KEGG: psl:Psta_2871 N-acetylglucosamine-6-phosphate deacetylase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase.
    
 0.572
lpxC
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
   
 0.558
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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