STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_0086Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] (409 aa)    
Predicted Functional Partners:
Isop_0087
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family.
 
  
 0.915
Isop_3125
COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: adg:Adeg_0074 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
 0.913
Isop_1639
Glutamine--scyllo-inositol transaminase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: rca:Rcas_0781 glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; PRIAM: Glutamine--scyllo-inositol transaminase; SPTR: Glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.754
Isop_0088
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region.
       0.620
Isop_1450
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR005888: IPR001509; KEGG: msl:Msil_2711 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.543
Isop_0089
N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255.
       0.435
Isop_0060
Nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: psl:Psta_1357 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose deh [...]
 
   
0.429
Isop_3038
Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018480: IPR018481; KEGG: tmt:Tmath_0189 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: Glycosyl transferase family 4.
  
  
 0.419
Isop_3093
Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: psl:Psta_4663 glycosyl transferase family 4; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase family 4; PFAM: Glycosyl transferase family 4.
  
  
 0.419
Isop_0054
Multi antimicrobial extrusion protein MatE; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002528; KEGG: gbm:Gbem_1791 polysaccharide biosynthesis protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein.
  
  
 0.406
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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