| node1 | node2 | node1 annotation | node2 annotation | score |
| Isop_0086 | Isop_0087 | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | 0.915 |
| Isop_0086 | Isop_0088 | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | 0.620 |
| Isop_0087 | Isop_0086 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | 0.915 |
| Isop_0087 | Isop_0088 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | 0.620 |
| Isop_0088 | Isop_0086 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | 0.620 |
| Isop_0088 | Isop_0087 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | 0.620 |
| Isop_0088 | Isop_0484 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1. | 0.692 |
| Isop_0088 | Isop_0972 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: nde:NIDE3566 putative peptidase; PFAM: peptidase M28; SPTR: Aminopeptidase; PFAM: Peptidase family M28. | 0.587 |
| Isop_0088 | Isop_1147 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | Amino acid/peptide transporter; COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR005279: IPR000109: IPR018456; KEGG: xal:XALc_Yp01 hypothetical amino acid/peptide transporter protein; PFAM: TGF-beta receptor type I/II extracellular region; SPTR: Di-/tripeptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: POT family; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial. | 0.532 |
| Isop_0088 | Isop_1372 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | Dipeptidyl-peptidase 7; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. | 0.513 |
| Isop_0088 | Isop_1883 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: rbi:RB2501_14084 probable aminopeptidase; PFAM: peptidase M28; SPTR: Peptidase M28; PFAM: Peptidase family M28. | 0.592 |
| Isop_0088 | Isop_2303 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR001478: IPR017441: IPR003137: IPR007484; KEGG: psl:Psta_3192 peptidase M28; PFAM: peptidase M28; protease-associated PA domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Probable aminopeptidase; PFAM: PA domain; PDZ domain (Also known as DHR or GLGF); Peptidase family M28. | 0.524 |
| Isop_0088 | Isop_2602 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | Glutamyl peptidase; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: ccs:CCNA_02753 aminoacyl peptidase; SPTR: Peptidase, S9A/B/C family, catalytic domain protein; PFAM: Prolyl oligopeptidase family. | 0.537 |
| Isop_0088 | Isop_3297 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | InterPro IPR000834; KEGG: sus:Acid_1533 peptidase M14, carboxypeptidase A; PFAM: peptidase M14 carboxypeptidase A; SPTR: Peptidase M14, carboxypeptidase A; PFAM: Zinc carboxypeptidase. | 0.566 |
| Isop_0484 | Isop_0088 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1. | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | 0.692 |
| Isop_0484 | Isop_0972 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1. | Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: nde:NIDE3566 putative peptidase; PFAM: peptidase M28; SPTR: Aminopeptidase; PFAM: Peptidase family M28. | 0.465 |
| Isop_0484 | Isop_1147 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1. | Amino acid/peptide transporter; COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR005279: IPR000109: IPR018456; KEGG: xal:XALc_Yp01 hypothetical amino acid/peptide transporter protein; PFAM: TGF-beta receptor type I/II extracellular region; SPTR: Di-/tripeptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: POT family; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial. | 0.461 |
| Isop_0484 | Isop_1883 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1. | Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: rbi:RB2501_14084 probable aminopeptidase; PFAM: peptidase M28; SPTR: Peptidase M28; PFAM: Peptidase family M28. | 0.506 |
| Isop_0484 | Isop_2303 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1. | Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR001478: IPR017441: IPR003137: IPR007484; KEGG: psl:Psta_3192 peptidase M28; PFAM: peptidase M28; protease-associated PA domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Probable aminopeptidase; PFAM: PA domain; PDZ domain (Also known as DHR or GLGF); Peptidase family M28. | 0.443 |
| Isop_0484 | Isop_3297 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1. | InterPro IPR000834; KEGG: sus:Acid_1533 peptidase M14, carboxypeptidase A; PFAM: peptidase M14 carboxypeptidase A; SPTR: Peptidase M14, carboxypeptidase A; PFAM: Zinc carboxypeptidase. | 0.401 |