| node1 | node2 | node1 annotation | node2 annotation | score |
| Isop_0067 | Isop_0089 | KEGG: ttr:Tter_2666 hypothetical protein; SPTR: Putative uncharacterized protein. | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | 0.558 |
| Isop_0086 | Isop_0087 | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | 0.915 |
| Isop_0086 | Isop_0088 | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | 0.620 |
| Isop_0086 | Isop_0089 | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | 0.435 |
| Isop_0087 | Isop_0086 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | 0.915 |
| Isop_0087 | Isop_0088 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | 0.620 |
| Isop_0087 | Isop_0089 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | 0.413 |
| Isop_0088 | Isop_0086 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | 0.620 |
| Isop_0088 | Isop_0087 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | 0.620 |
| Isop_0088 | Isop_0089 | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | 0.500 |
| Isop_0089 | Isop_0067 | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | KEGG: ttr:Tter_2666 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.558 |
| Isop_0089 | Isop_0086 | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...] | 0.435 |
| Isop_0089 | Isop_0087 | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family. | 0.413 |
| Isop_0089 | Isop_0088 | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region. | 0.500 |
| Isop_0089 | Isop_0090 | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000253: IPR000160; KEGG: afw:Anae109_4141 diguanylate cyclase; PFAM: GGDEF domain containing protein; Forkhead-associated protein; SMART: GGDEF domain containing protein; Forkhead-associated protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; FHA domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.566 |
| Isop_0089 | Isop_0323 | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | Glycoside hydrolase family 5; COGs: COG2730 Endoglucanase; InterPro IPR001547: IPR018087; KEGG: trq:TRQ2_1074 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 5; SPTR: Glycoside hydrolase family 5; PFAM: Cellulase (glycosyl hydrolase family 5); Belongs to the glycosyl hydrolase 5 (cellulase A) family. | 0.599 |
| Isop_0089 | Isop_0821 | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | Hypothetical protein; KEGG: cai:Caci_3165 ricin B lectin; SPTR: Putative uncharacterized protein. | 0.599 |
| Isop_0089 | Isop_3412 | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | KEGG: mbr:MONBRDRAFT_26897 hypothetical protein; SPTR: Predicted protein. | 0.599 |
| Isop_0090 | Isop_0089 | Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000253: IPR000160; KEGG: afw:Anae109_4141 diguanylate cyclase; PFAM: GGDEF domain containing protein; Forkhead-associated protein; SMART: GGDEF domain containing protein; Forkhead-associated protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; FHA domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | 0.566 |
| Isop_0323 | Isop_0089 | Glycoside hydrolase family 5; COGs: COG2730 Endoglucanase; InterPro IPR001547: IPR018087; KEGG: trq:TRQ2_1074 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 5; SPTR: Glycoside hydrolase family 5; PFAM: Cellulase (glycosyl hydrolase family 5); Belongs to the glycosyl hydrolase 5 (cellulase A) family. | N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. | 0.599 |