STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_0089N-acylglucosamine 2-epimerase; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR010819; KEGG: bts:Btus_0399 protein of unknown function DUF255; PFAM: N-acylglucosamine 2-epimerase; SPTR: Putative uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Protein of unknown function, DUF255. (909 aa)    
Predicted Functional Partners:
Isop_0323
Glycoside hydrolase family 5; COGs: COG2730 Endoglucanase; InterPro IPR001547: IPR018087; KEGG: trq:TRQ2_1074 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 5; SPTR: Glycoside hydrolase family 5; PFAM: Cellulase (glycosyl hydrolase family 5); Belongs to the glycosyl hydrolase 5 (cellulase A) family.
   
 
 0.599
Isop_0821
Hypothetical protein; KEGG: cai:Caci_3165 ricin B lectin; SPTR: Putative uncharacterized protein.
   
 
 0.599
Isop_3412
KEGG: mbr:MONBRDRAFT_26897 hypothetical protein; SPTR: Predicted protein.
   
 
 0.599
Isop_0090
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000253: IPR000160; KEGG: afw:Anae109_4141 diguanylate cyclase; PFAM: GGDEF domain containing protein; Forkhead-associated protein; SMART: GGDEF domain containing protein; Forkhead-associated protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; FHA domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
       0.566
Isop_0067
KEGG: ttr:Tter_2666 hypothetical protein; SPTR: Putative uncharacterized protein.
   
   0.558
Isop_0088
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region.
       0.500
Isop_0086
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...]
       0.435
Isop_0087
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mmi:MMAR_2310 UDP-glucose 4-epimerase, GalE5; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase, GalE5; manually curated; PFAM: NAD dependent epimerase/dehydratase family.
       0.413
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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