STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_0091Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: plm:Plim_3631 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel. (283 aa)    
Predicted Functional Partners:
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.780
Isop_0509
KEGG: plm:Plim_2156 transmembrane prediction; SPTR: Putative uncharacterized protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
  
     0.677
Isop_2339
Hypothetical protein; KEGG: rba:RB3324 signal peptide; SPTR: Putative uncharacterized protein.
  
     0.633
Isop_1874
Hypothetical protein; KEGG: dfe:Dfer_2054 signal peptide; SPTR: Membrane-bound dehydrogenase domain protein; PFAM: Trehalose utilisation.
  
     0.619
Isop_0042
Protein of unknown function DUF1549; COGs: COG2319 FOG: WD40 repeat; InterProIPR019782: IPR017986: IPR009056: IPR019781: IPR 003343: IPR011444: IPR001680; KEGG: plm:Plim_1151 protein of unknown function DUF1549; PFAM: protein of unknown function DUF1549; WD40 repeat, subgroup; Ig domain protein group 2 domain protein; SMART: Ig domain protein group 2 domain protein; WD-40 repeat-containing protein; SPTR: Putative uncharacterized protein; PFAM: WD domain, G-beta repeat; Protein of unknown function (DUF1549); Planctomycete cytochrome C; Protein of unknown function (DUF1553).
  
     0.600
Isop_0444
COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: phe:Phep_0342 dipeptidyl aminopeptidase/acylaminoacyl-peptidase; SPTR: Putative uncharacterized protein; PFAM: Prolyl oligopeptidase family.
  
     0.600
Isop_3237
Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: plm:Plim_0551 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Putative uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel.
  
     0.598
Isop_3555
LmbE family protein; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: rba:RB3342 hypothetical protein; PFAM: LmbE family protein; SPTR: Putative uncharacterized protein; PFAM: GlcNAc-PI de-N-acetylase.
  
     0.547
Isop_2914
Hypothetical protein; InterPro IPR017909; KEGG: psl:Psta_3531 peptidase domain protein; SPTR: Putative uncharacterized protein.
  
     0.533
Isop_1803
Acetyl xylan esterase; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR008391; KEGG: rba:RB5616 hypothetical protein; PFAM: Acetyl xylan esterase; SPTR: Putative uncharacterized protein; PFAM: Prolyl oligopeptidase family.
  
     0.530
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.