Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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Isop_0115Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: phe:Phep_3646 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Putative uncharacterized protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (386 aa)    
Predicted Functional Partners:
Isop_1330
Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307: IPR011418; KEGG: psl:Psta_1535 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; AP endonuclease 2 domain protein; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: AP endonuclease family 2 C terminus; Xylose isomerase-like TIM barrel.
 
    0.778
Isop_0595
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: rca:Rcas_2202 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.623
Isop_1887
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR006311: IPR017909; KEGG: rsl:RPSI07_2135 putative oxidoreductase; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.621
Isop_3114
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR006311: IPR017909: IPR019546: IPR000683; KEGG: plm:Plim_3765 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Twin-arginine translocation pathway, signal sequence, subgroup; SPTR: Oxidoreductase domain protein; PFAM: TAT (twin-arginine translocation) pathway signal sequence; Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
     0.592
Isop_0714
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterProIPR000683: IPR004104: IPR006311: IPR017909: IPR 017970; KEGG: sus:Acid_3950 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.569
Isop_2526
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_3510 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.550
Isop_2981
Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307: IPR011418; KEGG: rba:RB5053 hypothetical protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; AP endonuclease 2 domain protein; SPTR: Putative uncharacterized protein; PFAM: AP endonuclease family 2 C terminus; Xylose isomerase-like TIM barrel.
  
    0.507
Isop_0079
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: plm:Plim_2996 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.501
Isop_2337
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: psl:Psta_3890 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Probable NADH-dependent dyhydrogenase related protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
  
     0.463
Isop_0786
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: plm:Plim_2198 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
  
     0.424
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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