Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0181Hypothetical protein; COGs: COG1560 Lauroyl/myristoyl acyltransferase; KEGG: aeh:Mlg_2805 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; SPTR: Lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase. (439 aa)    
Predicted Functional Partners:
Isop_0180
Amino acid adenylation domain protein; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR010071: IPR020845: IPR000873; KEGG: eba:ebA4326 putative acyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative acyl-CoA synthetase; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-binding enzyme; TIGRFAM: amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family.
       0.637
Isop_0177
KEGG: eba:ebA4323 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.483
Isop_0178
KEGG: eba:ebA4323 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.483
Isop_0179
KEGG: eba:ebA4323 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.483
Isop_0131
KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR004800: IPR018506: IPR001347; KEGG: psl:Psta_0845 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein.
     
 0.454
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (22%) [HD]