STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_0184KEGG: psl:Psta_2531 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: DinB family. (188 aa)    
Predicted Functional Partners:
Isop_1951
InterPro IPR017941; KEGG: plm:Plim_0423 Rieske (2Fe-2S) domain protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Menaquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain.
  
    0.699
Isop_0635
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0348 Polyferredoxin; InterPro IPR017896: IPR017900; KEGG: hoh:Hoch_0561 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain.
  
  
 0.694
Isop_3520
KEGG: htu:Htur_4304 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.666
tadA
tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
  
 0.638
nuoD
NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
    0.635
Isop_0364
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137: IPR017900: IPR017896; KEGG: geo:Geob_1699 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
  
  
 0.632
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.623
Isop_0185
COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR018044: IPR001466: IPR002477: IPR001967; KEGG: psl:Psta_1647 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Peptidoglycan-binding domain 1 protein; beta-lactamase; SPTR: Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PFAM: Putative peptidoglycan binding domain; D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.583
Isop_1582
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006158: IPR006098: IPR006159: IPR006099; KEGG: mxa:MXAN_2263 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase, alpha subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
     
 0.516
Isop_1583
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099; KEGG: rru:Rru_A2480 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase, heterodimeric type, beta chain.
     
 0.516
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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