Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0246Hypothetical protein; COGs: COG2215 ABC-type uncharacterized transport system permease component; KEGG: cai:Caci_3988 high-affinity nickel-transporter; SPTR: High-affinity nickel-transporter; PFAM: High-affinity nickel-transport protein. (528 aa)    
Predicted Functional Partners:
Isop_0245
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: psl:Psta_0568 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator-like protein; PFAM: Response regulator receiver domain.
       0.773
Isop_0244
Protein of unknown function DUF1571; InterPro IPR011465; KEGG: cre:CHLREDRAFT_10029 fibrocystin-L-like protein; PFAM: protein of unknown function DUF1571; SPTR: Plus agglutinin; PFAM: Protein of unknown function (DUF1571).
       0.435
Isop_0247
InterPro IPR010496; KEGG: rmr:Rmar_1742 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
       0.431
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (20%) [HD]