STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (167 aa)    
Predicted Functional Partners:
msrB
methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase.
 
 0.990
Isop_2171
Glutaredoxin; COGs: COG0695 Glutaredoxin and related protein; InterPro IPR011767: IPR014025: IPR002109; KEGG: pde:Pden_2586 glutaredoxin 3; PFAM: glutaredoxin; SPTR: Glutaredoxin 3; PFAM: Glutaredoxin.
  
 
 0.787
Isop_0047
Protein-disulfide reductase; COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR017936; KEGG: plm:Plim_0535 cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: Cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region; Protein of unknown function, DUF255.
   
 
 0.772
Isop_2902
Peroxiredoxin; COGs: COG0386 Glutathione peroxidase; InterPro IPR000889; KEGG: sus:Acid_7250 glutathione peroxidase; PFAM: glutathione peroxidase; PRIAM: Peroxiredoxin; SPTR: Glutathione peroxidase; PFAM: Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 
 0.644
Isop_2379
Redoxin domain protein; InterPro IPR017937: IPR013740: IPR000866: IPR017936; KEGG: ote:Oter_0137 redoxin domain-containing protein; PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: AhpC/TSA family.
  
 0.599
Isop_1760
NHL repeat containing protein; COGs: COG3391 conserved hypothetical protein; InterPro IPR017936: IPR001258; KEGG: psl:Psta_3322 NHL repeat containing protein; PFAM: NHL repeat containing protein; SPTR: NHL repeat containing protein; PFAM: NHL repeat; AhpC/TSA family.
   
 0.544
Isop_0185
COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR018044: IPR001466: IPR002477: IPR001967; KEGG: psl:Psta_1647 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Peptidoglycan-binding domain 1 protein; beta-lactamase; SPTR: Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PFAM: Putative peptidoglycan binding domain; D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.516
Isop_0314
Redoxin domain protein; InterPro IPR013740: IPR009056: IPR017936; KEGG: psl:Psta_2862 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: Redoxin domain protein; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: Copper type II ascorbate-dependent monooxygenase, C-terminal domain; Redoxin.
   
 0.515
Isop_0577
Redoxin domain protein; InterPro IPR013740: IPR017936; KEGG: shn:Shewana3_1881 redoxin domain-containing protein; PFAM: Redoxin domain protein; SPTR: Thioredoxin-like protein; PFAM: AhpC/TSA family.
   
 0.515
Isop_0611
Redoxin domain protein; COGs: COG0526 Thiol-disulfide isomerase and thioredoxins; InterPro IPR013740: IPR017936: IPR017937: IPR006650; KEGG: son:SO_0269 thioredoxin, putative; PFAM: Redoxin domain protein; SPTR: Thioredoxin, putative; PFAM: Redoxin.
   
 0.515
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.