STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0256Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013342; KEGG: rba:RB10855 muconate cycloisomerase I; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Muconate cycloisomerase I; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain. (478 aa)    
Predicted Functional Partners:
Isop_0255
Alpha/beta hydrolase fold protein; COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: rba:RB10853 lysophospholipase; PFAM: alpha/beta hydrolase fold; SPTR: Probable lysophospholipase; PFAM: Putative lysophospholipase.
       0.780
Isop_0303
Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: rba:RB4366 hypothetical protein; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: Putative uncharacterized protein; PFAM: Macro domain.
   
   0.575
efp
Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
       0.562
Isop_1914
COGs: COG3375 conserved hypothetical protein; KEGG: tpe:Tpen_1785 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.483
Isop_0254
KEGG: tcr:510625.10 dispersed gene family protein 1 (DGF-1); SPTR: Dispersed gene family protein 1 (DGF-1), putative.
       0.476
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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