STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_0261COGs: COG0515 Serine/threonine protein kinase; InterProIPR019734: IPR000719: IPR013026: IPR017442: IPR 001440: IPR020635: IPR002290; KEGG: mno:Mnod_2431 peptidase C14 caspase catalytic subunit P20; PFAM: Serine/threonine-protein kinase-like domain; Tetratricopeptide TPR_1 repeat-containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; Tetratricopeptide repeat; SPTR: TPR domain protein; PFAM: Protein kinase domain; Tetratricopeptide repeat; TIGRFAM: DNA binding domain, excisionase family. (923 aa)    
Predicted Functional Partners:
Isop_3386
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045: IPR001932; KEGG: plm:Plim_2397 phosphoprotein phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: Protein phosphatase; PFAM: Protein phosphatase 2C.
 
   0.777
Isop_3004
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932: IPR014045: IPR010822; KEGG: psl:Psta_1567 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C.
 
   0.727
Isop_1435
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR017442: IPR017441: IPR008271: IPR 020635: IPR002290; KEGG: fal:FRAAL4418 putative serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Putative serine/threonine protein kinase; PFAM: Protein kinase domain.
  
     0.637
Isop_0125
InterPro IPR019734: IPR013026: IPR001440; KEGG: cyb:CYB_1571 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Tetratricopeptide repeat protein.
 
   0.616
Isop_2136
COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635: IPR002290: IPR017441: IPR008271: IPR 017442: IPR000719; KEGG: hoh:Hoch_1432 serine/threonine protein kinase with WD40 repeats; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Serine/threonine protein kinase with WD40 repeats; PFAM: Protein kinase domain.
  
     0.611
Isop_2182
COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635: IPR002290: IPR008271: IPR017442: IPR 005532: IPR000719; KEGG: rba:RB1892 serine/threonine protein kinase; PFAM: protein of unknown function DUF323; Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Serine/threonine protein kinase; PFAM: Protein kinase domain; Formylglycine-generating sulfatase enzyme.
 
    0.607
Isop_2015
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR020635: IPR002290: IPR017441: IPR 008271: IPR000719; KEGG: gob:Gobs_1752 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Serine/threonine protein kinase with PASTA sensor(S); PFAM: Protein kinase domain.
  
     0.595
Isop_3676
Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG0457 FOG: TPR repeat; InterPro IPR019734: IPR013026: IPR001440; KEGG: pcs:Pc22g03720 Pc22g03720; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Pc22g03720 protein; PFAM: Tetratricopeptide repeat.
 
 
 0.563
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.549
Isop_2985
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110: IPR020683; KEGG: sin:YN1551_2013 ankyrin; PFAM: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
 
 0.528
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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