STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
Isop_0264Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. (295 aa)    
Predicted Functional Partners:
Isop_0265
Protein of unknown function DUF167; COGs: COG1872 conserved hypothetical protein; InterPro IPR003746; KEGG: scl:sce8156 hypothetical protein; PFAM: protein of unknown function DUF167; SPTR: UPF0235 protein DehlyDRAFT_1349; PFAM: Uncharacterised ACR, YggU family COG1872; TIGRFAM: conserved hypothetical protein TIGR00251; Belongs to the UPF0235 family.
  
  
 0.712
rpmC
LSU ribosomal protein L29P; InterPro IPR001854; KEGG: psl:Psta_2608 ribosomal protein L29; PFAM: ribosomal protein L29; SPTR: Probable 50S ribosomal protein L29; TIGRFAM: ribosomal protein L29; PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
   
    0.617
rplX
LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
   
    0.616
Isop_2369
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
     0.587
rlmN
23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
     0.553
rpmJ
LSU ribosomal protein L36P; InterPro IPR000473; KEGG: ele:Elen_2808 ribosomal protein L36; PFAM: ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: ribosomal protein L36; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; Belongs to the bacterial ribosomal protein bL36 family.
  
    0.516
Isop_2948
Radical SAM domain protein; COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR007197: IPR004383; KEGG: ade:Adeh_4229 ribosomal RNA large subunit methyltransferase N; PFAM: Radical SAM domain protein; SPTR: Probable RNA methyltransferase Adeh_4229; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM enzyme, Cfr family; Belongs to the radical SAM superfamily. RlmN family.
 
     0.510
Isop_3517
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: plm:Plim_0648 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
 
     0.459
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
 
 
   0.426
Isop_0263
KEGG: tbr:Tb11.01.4480 hypothetical protein; SPTR: Predicted protein.
       0.416
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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